Reduced severity of arthritis in mice treated with Flt3L.
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A) Morphological changes in knee joint during mBSA arthritis development. JC = joint cavity, C = cartilage, S = synovitis, E = erosions. Scale bar = 100 μm B) Severity of arthritis in Flt3L-treated (mBSA + Flt3L, n = 22) and sham-treated (mBSA, n = 33) mice. Arthritis index was calculated as the sum of synovitis and destruction. Three independent experiments were preformed. C) Serum levels of mBSA specific IgG antibodies at day 28. D) Levels of IL-6 and TNF-α in the supernatant of unstimulated splenocytes isolated form Flt3L- and sham-treated mice. Data are presented as mean ± SEM and statistical significance was assessed using unpaired t-test. *PPP
创建时间：
2016-02-24
