CK2 alpha bound to unclosed Macrocycle
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CK2 alpha bound to unclosed Macrocycle Descriptor: 4-[5-[2-(2-hydroxyethyloxy)ethyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]pyrazolo[1,5-a]pyrimidin-3-yl]-2-oxidanyl-benzoic acid, Casein kinase II subunit alpha, SULFATE ION Authors: Kraemer, A, Hanke, T, Kurz, C, Celik, I, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2020-04-27 Release date: 2020-07-01 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor. Eur.J.Med.Chem., 208, 2020
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2020-04-27
