five

The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE148115
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The bone marrow microenvironment of leukemia plays a key role in leukemia progression, but its molecular complexity in pre-B acute lymphoblastic leukemia (B-ALL), the most common cancer in children, remains poorly understood. Here we use single-cell RNA sequencing to characterise the bone marrow microenvironment during B-ALL progression. Five samples were collected during B-ALL disease progression at days 0, 3, 6, 9 and 12
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2020-11-16
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