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PREVALENCE AND CLINICAL IMPACT OF MINORITY RESISTANT VARIANTS IN PATIENTS FAILING INTEGRASE INHIBITOR-BASED REGIMEN BY ULTRA-DEEP SEQUENCING

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NIAID Data Ecosystem2026-03-10 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA448668
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资源简介:
Integrase strand transfer inhibitors (INSTIs) are currently recommended byinternational guidelines as first-line therapy in antiretroviral (ARV)-naïve and experienced HIV-1infected patients. This study aimed at evaluating prevalence at failure of INSTI resistant variants andimpact of baseline minority resistant variants (MiRVs) on virological response to INSTI-basedregimen.
创建时间:
2018-04-04
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