A SIX6 reporter for studies of early optic development
收藏NIAID Data Ecosystem2026-03-12 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP326484
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资源简介：
Human pluripotent stem cells represent an exciting tool to investigate the mechanisms of human eye development and to build human models of retinal dystrophy. To explore the dynamics of early eye development in a carefully controlled setting and optimize this process, we have developed an eyefield expressed SIX6-GFP reporter that enables the systematic optimization of early eye-field development allowing the identification of conditions that favor early optic development. Overall design: Pooled day 65 retina cups (n>3/sample) were separated as either GFP- (n=4), GFP+ (n=4) or SIX6+/POU4F2+ (n=4) samples (total of 12 samples run for RNA-seq).
创建时间：
2021-09-02
