Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts

<p>This collection contains data from the Eastern Cooperative Oncology Group (ECOG) Clinical Trial <a title="" href="https://clinicaltrials.gov/study/NCT02933489">NCT02933489</a>, “Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts". Principal Investigator: Christopher Comstock.  It was sponsored by NCI and performed by the Eastern Cooperative Oncology Group under study number <strong>EA1141</strong>. This randomized phase II trial enrolled 1,516 subjects to study how well abbreviated breast magnetic resonance imaging (MRI) and digital tomosynthesis mammography work in detecting cancer in women with dense breasts. Imaging and clinical data from 500 of those subjects are being made available through this collection.</p><h3>Trial Outcomes</h3><p>Results of the trial have been reported in the following publication:</p><ul><li>Comstock CE, Gatsonis C, Newstead GM, Snyder BS, Gareen IF, Bergin JT, Rahbar H, Sung JS, Jacobs C, Harvey JA, Nicholson MH, Ward RC, Holt J, Prather A, Miller KD, Schnall MD, Kuhl CK. Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women With Dense Breasts Undergoing Screening. JAMA. 2020 Feb 25;323(8):746-756. doi: <a href="https://doi.org/10.1001/jama.2020.0572">10.1001/jama.2020.0572</a>. Erratum in: JAMA. 2020 Mar 24;323(12):1194. </li></ul>

<p>本数据集收录了来自东部合作肿瘤学组（Eastern Cooperative Oncology Group，ECOG）临床试验NCT02933489，“针对乳腺密度女性进行缩略乳腺MRI与数字断层合成摄影筛查”的数据。主要研究者为Christopher Comstock。该试验由NCI资助，在东部合作肿瘤学组的EA1141研究编号下进行。这是一项随机性II期试验，共招募了1,516名受试者，旨在研究缩略乳腺磁共振成像（MRI）与数字断层合成摄影在检测乳腺密度女性癌症中的有效性。本集合中提供了其中500名受试者的影像学及临床数据。</p><h3>试验结果</h3><p>该试验的结果已在以下出版物中报道：</p><ul><li>Comstock CE, Gatsonis C, Newstead GM, Snyder BS, Gareen IF, Bergin JT, Rahbar H, Sung JS, Jacobs C, Harvey JA, Nicholson MH, Ward RC, Holt J, Prather A, Miller KD, Schnall MD, Kuhl CK. 缩略乳腺MRI与数字乳腺断层合成摄影在乳腺密度女性筛查乳腺癌检测中的比较. JAMA. 2020年2月25日;323(8):746-756. doi: <a href="https://doi.org/10.1001/jama.2020.0572">10.1001/jama.2020.0572</a>. 更正于: JAMA. 2020年3月24日;323(12):1194.</li></ul>