Series of samples studying effect of knocking out RUNX1 (a.k.a. AML1) in mouse embryos at 8.5 and 12 days. Wildtype and knockout animals at the two time points were generated and all conditions done

NIAID Data Ecosystem10

Maintenance of mammary epithelial phenotype by AML1/RUNX1 through mitotic gene bookmarking. Maintenance of mammary epithelial phenotype by AML1/RUNX1 through mitotic gene bookmarking

Genetic and epigenetic changes in mammary epithelial cells facilitate epithelial-to-mesenchymal transition (EMT) which leads to invasion and metastasis. RUNX1 is a phenotypic transcription factor pivo

NIAID Data Ecosystem10

Expression data from mouse embryo. Mus musculus

To understand the molecular mechanism by which regulate skeletal development, we attempted to identify transcription factors that were highly expressed in developing cartilage during the embryonic sta

NIAID Data Ecosystem20

RUNX1 (AML1) knockout in mouse embryo. Mus musculus