Crystal structure of PDE10A2 with fragment ZT0120 (7-chloroquinolin-4-ol)
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Crystal structure of PDE10A2 with fragment ZT0120 (7-chloroquinolin-4-ol) Descriptor: 7-chloroquinolin-4-ol, NICKEL (II) ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Authors: Sridhar, V, Badger, J, Logan, C, Chie-Leon, B, NIenaber, V. Deposit date: 2013-09-17 Release date: 2014-05-14 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography. J Biomol Screen, 19, 2014
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2013-09-17
