An Improved Synthesis of (±)-<i>N</i>′-Nitrosonornicotine 5′-Acetate
收藏NIAID Data Ecosystem2026-03-06 收录
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资源简介：
A concise and efficient route to (±)-N′-nitrosonornicotine 5′-acetate (NNN-5′-OAc), a stable precursor of the active metabolite 5′-hydroxy(±)-N′-nitrosonornicotine NNN-5′-OH is reported. The synthesis utilizes sulfinimine chemistry to give (±)-NNN-5′-OAc in 26% yield over 4 steps.
创建时间：
2016-02-26
