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Expression data of miRNAs and lncRNAs from the lumbosacral spinal cord of fetal rats with anorectal malformations in embryonic day 19

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many dysregulated miRNAs and lncRNAs as the primary factor could be play an important role in the development of lumbosacral spinal cord of fetal rats with anorectal malformations in embryonic day 17.High-throughput sequencing was utilized to reveal the expression of non-coding RNAs underlying the development of anorectal malformations.

在胚胎第17天的肛门直肠畸形胎鼠中,大量异常表达的微小RNA(microRNA, miRNA)与长链非编码RNA(long non-coding RNA, lncRNA)作为核心影响因素,可在其腰骶脊髓发育过程中发挥重要作用。本研究采用高通量测序技术,揭示了肛门直肠畸形发育进程中相关非编码RNA的表达特征。

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