Comparative biodistribution of NODAGA-Z<sub>HER2:S1</sub>, NOTA-Z<sub>HER2:S1</sub> and DOTA-Z<sub>HER2:S1</sub> labelled with gallium-68 and indium-111 after intravenous injection in female BALB/C nu/nu mice bearing SKOV-3 xenografts.
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Data are presented as an average % IA/g and standard deviation for four mice. Data concerning bone from one mice injected with 68Ga-NOTA-ZHER2:S1 and bone and muscle form one mice injected with 68Ga-NODAGA-ZHER2:S1were excluded due to low counts. asignificant difference (p<0.05) between 68Ga-DOTA-ZHER2:S1 and 111In-DOTA-ZHER2:S1. bsignificant difference (p<0.05) between 68Ga-NOTA-ZHER2:S1 and 111In-NOTA-ZHER2:S1. csignificant difference (p<0.05) between 68Ga-NODAGA-ZHER2:S1 and 111In-NODAGA-ZHER2:S1. dsignificant difference (p<0.05) between 68Ga-DOTA-ZHER2:S1 and 68Ga-NOTA-ZHER2:S1. esignificant difference (p<0.05) between 68Ga-NOTA-ZHER2:S1 and 68Ga-NODAGA-ZHER2:S1. fsignificant difference (p<0.05) between 68Ga-NODAGA-ZHER2:S1 and 68Ga-DOTA-ZHER2:S1. *Data for gastrointestinal (GI) tract and carcass are presented as %IA per whole organ.
