Impact of cognitive performance and normal aging on transcriptomic changes in the prefrontal cortex of rats. Impact of cognitive performance and normal aging on transcriptomic changes in the prefrontal cortex of rats

We investigated how cognitive stimulation impacts gene expression in the prefrontal cortex (PFC), a brain region known to regulate higher cognitive functions including the control of attention, in young and aged rats. Overall design: 2x2 design: 2 (cognitive performance [2 levels: performing, non performing) x 2 (age [2 levels: young, old])