Application of DENV RVPs to clinical serum samples.
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Longitudinal serum samples taken at 3, 6, 12 and 18 months post-symptom onset from two primary DENV-1, one primary DENV-2, two primary DENV-3, and one secondary DENV-2 infection were obtained from naturally infected patients in Nicaragua. The serum representing secondary infection was derived from a patient that was last infected by DENV-2, as determined by RT-PCR and virus isolation. Each serum was used in neutralization assays against each DENV serotype. ‘
创建时间：
2015-12-02
