ARM binds to APC and AXN in the 'destruction complex'
收藏reactome.org2025-03-26 收录
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Phosphorylated APC (APC/APC2) and Axin (AXN) are able to bind cytoplasmic Armadillo (ARM) more strongly. This now brings ARM into the 'destruction complex' and within reach of the complexed kinases.
磷酸化APC(APC/APC2)及Axin(AXN)能够与细胞质中的Armadillo(ARM)结合力更强。此过程将ARM引入‘降解复合物’之中,使其能够触及复合的激酶。
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