Timp4

Predicted to enable metalloendopeptidase inhibitor activity and zinc ion binding activity. Acts upstream of or within Notch signaling pathway. Predicted to be located in sarcomere. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including brain ventricular layer; genitourinary system; hemolymphoid system gland; musculature; and ventral grey horn. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human TIMP4 (TIMP metallopeptidase inhibitor 4). [provided by Alliance of Genome Resources, Nov 2024]

预测具有金属内肽酶抑制剂活性和锌离子结合活性。在Notch信号通路的上游或通路内发挥作用。预测定位于肌节。预测在细胞外基质和细胞外空间中活性。在多个结构中表达，包括脑室层；泌尿生殖系统；血淋巴系统腺体；肌肉组织；以及腹侧灰质束。该基因的人类同源基因与肾母细胞瘤有关。与人类TIMP4（金属肽酶抑制剂4）同源。[由基因组资源联盟提供，2024年11月]