five

ysblcc sox2

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NIAID Data Ecosystem2026-03-12 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/ERP000115
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资源简介:
This project focuses on determining the genomic changes that gave rise to two deaf and balance-impaired allelic Sox2 mouse mutants using sequencing, Light coat and circling (Lcc) and Yellow submarine (Ysb). Lcc and Ysb are both regulatory alleles of Sox2 on chromosome 3 in which otic-specific transcription is compromised. In Lcc/Lcc Sox2 expression is severely reduced by loss or translocation of Sox2 otic-specific regulatory elements.
创建时间:
2021-02-04
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