Crystal structure of bruton's tyrosine kinase mutant V555R in complex with dasatinib
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Crystal structure of bruton's tyrosine kinase mutant V555R in complex with dasatinib Descriptor: N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Tyrosine-protein kinase BTK Authors: Davies, D.R, Staker, B.L. Deposit date: 2010-08-10 Release date: 2010-11-03 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A novel, specific Btk inhibitor antagonizes BCR and Fc[gamma]R signaling and suppresses inflammatory arthritis To be Published
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2010-08-10
