Crystal structure of HCV NS3/4A R155K protease complexed with compound 4
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Crystal structure of HCV NS3/4A R155K protease complexed with compound 4 Descriptor: (2R,6S,7E,10E,13aR,14aR,16aS)-2-{[7-methoxy-8-methyl-2-(propan-2-yloxy)quinolin-4-yl]oxy}-N-[(1-methylcyclopropyl)sulfonyl]-6-{[(1-methyl-1H-pyrazol-3-yl)carbonyl]amino}-5,16-dioxo-1,2,3,6,9,12,13,13a,14,15,16,16a-dodecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide, Genome polyprotein, HCV non-structural protein 4A, ... Authors: Lemke, C.T. Deposit date: 2012-11-23 Release date: 2013-01-02 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.9001 Å) Cite: Molecular Mechanism by Which a Potent Hepatitis C Virus NS3-NS4A Protease Inhibitor Overcomes Emergence of Resistance. J.Biol.Chem., 288, 2013
创建时间：
2012-11-23
