T47D Breast cancer cell line ChIP-seq data. T47D Breast cancer cell line ChIP-seq data
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA415426
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资源简介：
We performed genome-wide PADI2 ChIP seq experiments in T47D cell lines and also RNP2 ChIP seq in T47D cells only expressing HA Tagged amanitin resistant wild type in comparison to R1810A mutant form of RNAP2. Overall design: We designed experiment to perform genome wide PADI2 ChIP sequencing in T47D cells as in biological replicates .We find that PADI2 deiminates R1810 at CTD (C-terminal domian ) of RNAP2 , Therefore in order to investigate precise effect of the RNAP2 R1810A mutantion , we performed the RNAP2 ChIP seq by using the HA tagged antibody after expressing the amanitin resistant HA - tagged wild type and mutant form of RNAP2 .
创建时间：
2017-10-23
