The loss of muscle mass in alcoholic myopathy may reflect alcohol inhibition of myogenic cell differentiation into myotubes. Here, using a high content imaging system we show that ethanol inhibits C2C
Several cell cycle genes were altered between Dll1+ and Dll1- population of tumor cells Overall design: Examination of MMTV-PyMT, Dll1-GFP+ (n=2) and MMTV-PyMT, Dll1-GFP-(n=2) tumors; MMTV-PyMT, Dll1
Neural tube defects (NTDs) are common birth defects in humans and show an unexplained female bias. Female mice lacking the tumor suppressor p53 display NTDs with incomplete penetrance. We found that t
Purpose: To investigate the impact of oncogenic Notch on the 3D genome organization of cancer cells. Methods: We generated cohesin HiChIP and 1D epigenomic data sets in two different Notch-dependent c
