KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate Into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

NIAID Data Ecosystem2026-03-11 收录

T细胞免疫学

免疫记忆分化

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110707 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2019-03-21

Expression data from innate and conventional CD8+ T cell populations from naïve CXCR3-GFP Reporter mice

T细胞免疫学

基因表达谱分析

Innate CD8+ T cells are a heterogeneous population with developmental pathways distinct from conventional CD8+ T cells. Their biology, classification and functions remain incompletely understood. We r

NIAID Data Ecosystem50

Single cell transcriptomic analysis (InDrops) of mouse FoxP3- CD4+ Tconv cells and FoxP3+ regulatory CD4+ T cells isolated from secondary lymphoid organs. Single cell transcriptomic analysis (InDrops) of mouse FoxP3- CD4+ Tconv cells and FoxP3+ regulatory CD4+ T cells isolated from secondary lymphoid organs

单细胞转录组学

T细胞免疫学

Single cell transcriptomic analysis (InDrops) of mouse FoxP3- CD4+ Tconv cells and FoxP3+ regulatory CD4+ T cells isolated from secondary lymphoid organs Overall design: Single cells were sorted by fl

NIAID Data Ecosystem40

Transcriptomic profiling of naïve and memory phenotype CD8 T cells in Dock2-deficient mice. Transcriptomic profiling of naïve and memory phenotype CD8 T cells in Dock2-deficient mice

T细胞免疫学

转录组学分析

Transcriptomic data linked to our study showing that DOCK2 sets the threshold for entry into the virtual memory CD8+ T cell compartment by negatively regulating tonic TCR triggering Overall design: RN

NIAID Data Ecosystem10

RNA sequencing

转录组学

T细胞免疫学

To systematically explore the molecular mechanism underlying the proliferation defect, we performed RNA-sequencing analysis on the naive and in vitro activated T cells

NIAID Data Ecosystem40

Acquisition of optimal human follicular helper CD4 T cell function is defined by specific molecular, positional and TCR dynamic signature. Acquisition of optimal human follicular helper CD4 T cell function is defined by specific molecular, positional and TCR dynamic signature

T细胞免疫学

转录组特征

The purpose of this study was to study TFH cells and their transitionaing Status and its association with positioning in the Germinal Center. We observed significant transcriptomic signatures associat

NIAID Data Ecosystem30

KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate Into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

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