Immune cell-type composition changes with age, potentially weakening the response to infectious diseases. Profiling epigenetics marks of immune cells can help us understand the relationship with disea
In this study, we combined the MeDIP-Seq and MRE-Seq data of 6 ADU (active disease, untreated) and 5 HC (health control) samples to obtatin the differentially methylated regions (DMRs) between ADU and
DNA methylation analysis of DNA samples from total WBC collection The DNA samples from each subject was first subject to bisulfite conversion, followed by sample preparation and microarray experiment.
This dataset includes reproducible code for the two applications related to the 'MethylDetectR' software. These .R files are included as 'MethylDetectR - Calculate Your Scores.R' and 'MethylDetectR.R'
Myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML) are characterized by mutations in epigenetic modifiers and aberrant DNA methylation. DNA methyltransferase inhibitors (DMTis) are u