SOX7 and ETS factors regulate an endothelial transcriptional program during vascular development. Mus musculus

Vascular development involves complex changes in gene expression necessary to dictate the behaviour of differentiating endothelial cells within the emerging vascular network. However, the transcriptional programs regulating vascular development are poorly understood. Here we use a microarray approach to profile the genes regulated in response to SOX7 overexpression. Overall design: CD41 hematopoietic precursors (HPCs) were treated with and without dox for 12 and 24 hours in duplicate