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Syngergistic Anti-tumor Effects between GLA and X-ray Radiation

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE178553
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Nanostring gene expression analysis using tumors from mice treated with GLA, X-ray radiation or the combination of GLA and radiation showed that the combination of GLA and radiation has synergistic effect in modulating the tumor micronenvironment. Mice with A20 tumors received intratumoral injection of TLR4 agonist GLA (GLA-SE 10ug), X-ray radiation (RT), or GLA plus RT. Control mice received intratumoral injection of PBS. Tumors were collected and RNA was extracted for nanostring gene expression analysis using the mouse panCancer Immune Profiling panel.
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2021-12-23
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