ChIP-seq of CD117-positive primary hematopoietic precursor cell from Meer mice that carry a leukemogenic knock-in of an inducible ENL-ER portion into the mouse Mll locus. ChIP-seq of CD117-positive primary hematopoietic precursor cell from Meer mice that carry a leukemogenic knock-in of an inducible ENL-ER portion into the mouse Mll locus

This ChIP-seq experiment was done to investigate the global distribution of H2A ubiquitination (a hallmark of polycomb mediated repression) and H2B ubiquitination (introduced by PAF-complex associated ubiquitin ligases and connected to active transcription) in Meer cells. Meer cells are primary cells transformed by a knock-in of an inducible Mll-ENL oncogene.