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The role of PTENα in brain. The role of PTENα in brain

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA998053
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In contrast to the ubiquitous expression profile of PTEN, PTENα is predominantly expressed in brain. To study the biological function of PTENα in brain, we employed LCMV to induce murine viral encephalitis model. Through single cell RNA sequencing, we revealed the immunological function of PTENα during viral infection in the brain. Overall design: The cortex from infected wild-type and Ptenα-specific deficient mice on day 7 after intracranial injection of LCMV-Cl13 were isolated and dissociated. Cells were pooled by 10x Genomics platform.
创建时间:
2023-07-24
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