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ATAC-seq of antigen-specific memory CD8+ T cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP528542
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Aging trajectories of antigen-specific memory T cells are heterogenous and complex but incompletely understood. We use single-cell sequencing of EBV (Epstein Barr virus)- or VZV (Varicella Zoster virus)-antigen specific T cells of younger or older adults to analyze memory T cell heterogeneity in early and late life. Overall design: Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) performed on flow extracted for CM, EM, TEMRA, EBV-specific CD8 T cells. This study includes a reanalysis of 15 Samples from GSE101609. *************************************************************** The table below lists GEO accessions reanalyzed for this study. ***************************************************************
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2025-07-30
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