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DNA double-strand breaks and 3D chromatin conformation (Hi-C, 4C-seq, ChIP-seq)

ChEBI2021-01-29 更新2026-07-12 收录

三维基因组学

DNA损伤修复

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-8851 数据链接链接失效反馈

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DNA double-strand breaks and 3D chromatin conformation (Hi-C, 4C-seq, ChIP-seq)

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创建时间：

2021-01-29

三维基因组学

染色体结构

GAMinG script (python) and sequence file (.dat) to prepare files to run molecular dynamics in GROMACS (see ndb.rice.edu for more info regarding how to run the simulations). Two .hic maps and two sampl

NIAID Data Ecosystem50

WRNIP1 is recruited to DNA interstrand crosslinks and promotes repair

DNA损伤修复

DNA相互作用

Mass spectrometry data relating to Figure 1 and Table S1.

NIAID Data Ecosystem40

Additional file 3 of LAP2α preserves genome integrity through assisting RPA deposition on damaged chromatin

蛋白质质谱分析

DNA损伤修复

Additional file 3: Table S2. Mass spectrometry analysis of LAP2α-containing protein complexes.

Figshare2024-02-20 更新20

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink with Manganese in the active site

DNA损伤修复

结构生物学

Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink with Manganese in the active site Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-

Protein Data Bank Japan2023-10-11 更新40

DNA double-strand breaks and 3D chromatin conformation (Hi-C, 4C-seq, ChIP-seq)

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