Crystal structure of HCV NS3/4A protease variant Y56H in complex with danoprevir
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal structure of HCV NS3/4A protease variant Y56H in complex with danoprevir Descriptor: (2R,6S,12Z,13aS,14aR,16aS)-6-[(tert-butoxycarbonyl)amino]-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxo-1,2,3,5,6,7,8 ,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoro-2H-isoindole-2-carboxylate, GLYCEROL, NS3 protease, ... Authors: Matthew, A.N, Schiffer, C.A. Deposit date: 2018-01-08 Release date: 2019-01-16 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.179 Å) Cite: Clinical signature variant of HCV NS3/4A protease uses a novel mechanism to confer resistance To be Published
创建时间:
2018-01-08



