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SuperFi-Cas9 exhibits extremely high fidelity but reduced activity in mammalian cells

NIAID Data Ecosystem2026-03-13 收录

基因编辑优化

CRISPR-Cas9

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA876837 数据链接链接失效反馈

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资源简介：

SuperFi-Cas9 exhibits extremely high fidelity but reduced activity in mammalian cells

应用场景：

创建时间：

2022-09-05

单细胞CRISPR筛选

基因编辑优化

The combination of single-cell RNA sequencing with CRISPR inhibition/activation provides a high-throughput approach to simultaneously study the effects of hundreds if not thousands of gene perturbatio

NIAID Data Ecosystem90

Structure of a protein from bacteria

蛋白质结构解析

CRISPR-Cas9

Structure of a protein from bacteria Descriptor: 100AA, CRISPR-associated endonuclease Cas9, DNA (28-MER), ... Authors: Liu, H, Zhu, Y, Huang, Z. Deposit date: 2021-04-07 Release date: 2021-07-28 Last

Protein Data Bank Japan2023-11-29 更新60

A Cas-Embedding Strategy for Minimizing Off-Target Effects of DNA Base Editors. Homo sapiens

基因编辑脱靶效应

CRISPR-Cas9

A Cas-Embedding Strategy for Minimizing Off-Target Effects of DNA Base Editors

NIAID Data Ecosystem30

MOESM2 of Engineering Aspergillus niger for galactaric acid production: elimination of galactaric acid catabolism by using RNA sequencing and CRISPR/Cas9

基因编辑

CRISPR-Cas9

Additional file 2: Table S2. DNA primer and sgRNA sequences used in the study.

DataCite Commons2024-12-13 更新80

Optimization of T-DNA architecture for Cas9-mediated mutagenesis in Arabidopsis

植物基因编辑优化

CRISPR-Cas9

Bacterial CRISPR systems have been widely adopted to create operator-specified site-specific nucleases. Such nuclease action commonly results in loss-of-function alleles, facilitating functional analy

Figshare2019-01-09 更新60

SuperFi-Cas9 exhibits extremely high fidelity but reduced activity in mammalian cells

资源简介：

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