Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine Descriptor: 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine, Beta-glucuronidase, Maltose/maltodextrin-binding periplasmic protein Authors: Wallace, B.D, Redinbo, M.R. Deposit date: 2018-04-04 Release date: 2019-04-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Targeted inhibition of gut bacterial beta-glucuronidase activity enhances anticancer drug efficacy. Proc.Natl.Acad.Sci.USA, 2020
创建时间：
2018-04-04
