Combined effects of MK-1775 and gemcitabine were quantified with the Chou and Talalay combination index (CI) method [14].
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The CI used for drug combination analyses was determined by the isobologram equation. Ranking symbols (+/−) indicate average calculated Chou and Talalay combination index (CI) range (+++, synergism; ++++, strong synergism).
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2015-12-02



