five

Cereblon in complex with DDB1, CC-885, and GSPT1

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5hxb
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Cereblon in complex with DDB1, CC-885, and GSPT1 Descriptor: 1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ... Authors: Chamberlain, P.P, Matyskiela, M, Pagarigan, B. Deposit date: 2016-01-30 Release date: 2016-06-29 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.6 Å) Cite: A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase. Nature, 535, 2016
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2016-01-30
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