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Effect of short-term prescription opioids on DNA methylation of the OPRM1 promoter

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NIAID Data Ecosystem2026-03-11 收录
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Evaluate the effect of short-term use of precribed opioids on DNA methylation Genome-wide DNA methylation was assayed in a cohort of opioid-naïve participants who underwent standard dental surgery followed by opioid self-administration. Saliva samples were collected longitudinally before surgery (visit 1), and at two postsurgery visits at 2.7 ± 1.5 days (visit 2), and 39 ± 10 days (visit 3) after the discontinuation of opioid analgesics.

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2020-06-16
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