PSEN1

ENCODES a protein that exhibits aspartic endopeptidase activity, intramembrane cleaving (ortholog); endopeptidase activity (ortholog); peptidase activity (ortholog); INVOLVED IN amyloid precursor protein catabolic process (ortholog); amyloid precursor protein metabolic process (ortholog); amyloid-beta formation (ortholog); PARTICIPATES IN Notch signaling pathway; syndecan signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 3 (ortholog); Alzheimer's disease 4 (ortholog); FOUND IN aggresome (ortholog); cell surface (ortholog); dendrite (ortholog)

编码一种表现出天冬氨酸内肽酶活性的蛋白质，跨膜切割（同源）；内肽酶活性（同源）；肽酶活性（同源）；参与淀粉样前体蛋白的代谢过程（同源）；淀粉样前体蛋白的代谢过程（同源）；淀粉样-β的形成（同源）；参与 notch 信号通路；syndecan 信号通路；与阿尔茨海默病（同源）；阿尔茨海默病 3（同源）；阿尔茨海默病 4（同源）；存在于聚合体（同源）；细胞表面（同源）；树突（同源）