FAPLTBRpreclinical_ST_publication_data

Data related to the publication "FAP-Targeted LTBR Agonist Drives HEV Differentiation and Immune Niche Formation for Improved Immunotherapy Response in Solid Tumours" by Bianchi et al. 2026 Contains: Spatial transcriptomics data adata_concat_qc_filtered.h5ad concatenated and filtered data clustering_results_harmony_deconv_bbknn.h5ad Harmony integrated data, including annotations post deconvolution results deconvolution_bbknn_celltype2_updated_v1_c2l_sp.h5ad Deconvolution results at cell type annotation level 2 (broad annotation) ScRNA-seq data used for deconvolution of the spatial transcriptomics data FAP_LTBR_scseqref_standard_workflow_besca2.annotated.h5ad - integrated scRNA-seq data across multiple mouse models, used as a reference for deconvolution Analysis notebooks are available under https://github.com/bedapub/FAPLTBRpreclinical_ST_publication