Crystal structure of protease inhibitor, MIT-1-AC87 in complex with wild type HIV-1 protease
收藏Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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Crystal structure of protease inhibitor, MIT-1-AC87 in complex with wild type HIV-1 protease Descriptor: (2E)-N-[(1S,2R)-1-BENZYL-2-HYDROXY-3-{(2-THIENYLMETHYL)[(2,4,5-TRIFLUOROPHENYL)SULFONYL]AMINO}PROPYL]-4,4,4-TRIFLUORO-3-METHYLBUT-2-ENAMIDE, PHOSPHATE ION, Protease Authors: Schiffer, C.A, Nalam, M.N.L. Deposit date: 2007-07-03 Release date: 2008-04-22 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.85 Å) Cite: HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. J.Am.Chem.Soc., 130, 2008
创建时间:
2007-07-03



