A Biomimetic Strategy to Access the Silybins: Total Synthesis of (−)-Isosilybin A
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https://figshare.com/articles/dataset/A_Biomimetic_Strategy_to_Access_the_Silybins_Total_Synthesis_of_Isosilybin_A/2046450
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资源简介：
We report the first asymmetric, total
synthesis of (−)-isosilybin
A. A late-stage catalytic biomimetic cyclization of a highly functionalized
chalcone is employed to form the characteristic benzopyranone ring.
A robust and flexible approach to this chalcone provides an entry
to the preparation of the entire isomeric family of silybin natural
products.
创建时间：
2015-12-17
