Human aldose reductase complexed with IDD 740 inhibitor
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https://pdbj.org/mine/summary/3g5e
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Human aldose reductase complexed with IDD 740 inhibitor Descriptor: 2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid, Aldose reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Podjarny, A.D, Van Zandt, M.C. Deposit date: 2009-02-05 Release date: 2009-03-24 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications. Bioorg.Med.Chem.Lett., 19, 2009
创建时间：
2009-02-05
