RNA-seq of miR-146a-5p overexpressing T24 human bladder cancer cells

We established stable miR-146a-5p overexpression T24 cells, then performed transcriptome profiling of miR-146a-5p overexpressing cells compared to control T24 cells to detect the molecular mechanisms of the miR-146a-5p’s effect on bladder cancer cells. T24 human bladder cells were transfected with a scramble control or with a mimic for the tumor suppressor miRNA, miR-146a-5p and following validation of miRNA expression, were subjected to gene expression profiling