Human thyroid hormone receptor alpha ligand binding domain in complex with beta-selective agonist ALG-055009
收藏Protein Data Bank Japan2024-09-25 更新2026-06-30 收录
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Human thyroid hormone receptor alpha ligand binding domain in complex with beta-selective agonist ALG-055009 Descriptor: 6-azanyl-2-[3,5-bis(chloranyl)-4-[(6-oxidanylidene-5-propan-2-yl-1~{H}-pyridazin-3-yl)oxy]phenyl]-1,2,4-triazine-3,5-dione, Isoform Alpha-1 of Thyroid hormone receptor alpha, SULFATE ION Authors: Lammens, A, Maskos, K, Stoycheva, A.D, McGowan, D.C. Deposit date: 2024-01-18 Release date: 2024-09-11 Last modified: 2024-09-25 Method: X-RAY DIFFRACTION (2.74 Å) Cite: Discovery and Preclinical Profile of ALG-055009, a Potent and Selective Thyroid Hormone Receptor Beta (THR-beta ) Agonist for the Treatment of MASH. J.Med.Chem., 67, 2024
创建时间：
2024-01-18
