HCV NS3-4A protease domain complexed with a ketoamide inhibitor, SCH446211
收藏Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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https://pdbj.org/mine/summary/2fm2
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HCV NS3-4A protease domain complexed with a ketoamide inhibitor, SCH446211 Descriptor: BETA-MERCAPTOETHANOL, NS3 protease/helicase, NS4a protein, ... Authors: Yi, M, Tong, X, Skelton, A, Chase, R, Chen, T, Prongay, A, Bogen, S.L, Saksena, A.K, Njoroge, F.G, Veselenak, R.L, Pyles, R.B, Bourne, N, Malcolm, B.A, Lemon, S.M. Deposit date: 2006-01-06 Release date: 2006-02-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations J.Biol.Chem., 281, 2006
创建时间:
2006-01-06



