Association of technical and clinical parameters with fHb and LDH as a marker for hemolysis in vvECMO therapy.

a p-values refer to the linear mixed model based on ranks with the respective continuous parameter as independent and fHb or LDH as dependent variable. Respective p-values were mentioned in the text.b p-values refer to the linear mixed model based on ranks with the respective categorical parameter as independent and fHb or LDH as dependent variable (respective p-values were mentioned in the text). Pairwise comparisons (all vs. control) were only performed in case of a significant main effect (p≤0.05).c Single-lumen backflow (diameter, 15, 17, 19, 21 Fr), dual-lumen cannulae (Avalon 23, 27 Fr) (all Maquet), Twinport 24 Fr (Novalung).d bacterial, viral, fungal, aspiration pneumonia, H1N1 infection.e other pathologies (pulmonary fibrosis, pulmonary hypertension, extensive bronchiectasis, pulmonary bleeding, tracheal laceration).RBC, red blood cells (one RBC contained 300 ml volume); CVVHF, continuous venovenous hemofiltration. fHb, free hemoglobin; LDH, lactate dehydrogenase; Fr, French.Association of technical and clinical parameters with fHb and LDH as a marker for hemolysis in vvECMO therapy.