Supplementary Table 1: Patterns of Use of Reflectance Confocal Microscopy at a Tertiary Referral Dermatology Clinic

Supplementary Table 1
Clinical tracking of diagnostic lesions imaged with RCM: The lesions included in the primary three clinical concern categories (suspected diseases) for which RCM imaging was performed. We show the clinical concern of the lesion, the RCM impression, management decision, and the pathology result of the lesion if and when it is biopsied. Lesions were considered benign if biopsy proven or continued follow-up, and malignant only if biopsy proven. Indeterminate lesions did not have any RCM features diagnostic of a benign or malignant process and therefore were classified as intermediate. The positive predictive value for melanoma was 47%, between 50-79% for BCC (due to empirically treated lesions), and between 31-69% for SCC (due to empirically treated lesions). The negative predictive value is 97% for melanoma, 80-88% for BCC (due to empirically treated lesions), and 83% for SCC.