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PAF1 Drives Pancreatic Cancer Oncogenesis by Promoting Stemness via PHF5A/DDX3 Sub-complex (ChIP-seq). PAF1 Drives Pancreatic Cancer Oncogenesis by Promoting Stemness via PHF5A/DDX3 Sub-complex (ChIP-seq)

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NIAID Data Ecosystem2026-04-25 收录
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In this study, we established that PAF1 is critical for pancreatic tumorigenesis, and CSC-driven tumor maintenance because depletion of PAF1 resulted in significantly less tumor burden and reduction in CSC populations. Overall design: Chromatin immunoprecipitation was performed using PAF1 and PHF5A antibodies; and IgG antibody was used as control

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2020-01-28
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