five

A longitudinal study on aggressive transformation of FL to DHL via whole genome sequencing

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA866386
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Follicular lymphoma (FL) transformed double hit lymphoma (DHL) is a very aggressive class of non-Hodgkin B cell lymphoma (B-NHL). However, whole genome level genetic alteration during the transformation is still not clear.To study the driver of aggressive transformation from low grade FL to high grade diffused large B cell lymphoma, we performed WGS on FL tissues and paired DHL tissues from 8 patients who suffered from FL to DHL aggressive transformation.
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2022-08-05
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