Effect of RCOR2 in cancer cell stemness and immune evasion

To investigate the function of RCOR2 in cancer cell stemness and immune evasion, we established RCOR2-KO MDA-MB-231 cells by CRISPR-Cas9. We then performed gene expression profiling analysis using data obtained from RNA-seq of the parental cells as well as two independent KO cell lines. Two biological repeats were applied for each cell line. Comparative gene expression profiling analysis of RNA-seq data for parental and RCOR2-KO MDA-MB-231 cells.