Transcription profiling by array of mice tissues comparing microRNA-22 KO to wildtype

To explore the role of miR-22 targeting in different tissues in adult mice, we generated a miR-22 null mouse model and profiled expression in muscle, heart, liver, kidney and white adipose tissue.为探究miR-22（microRNA-22）靶向调控在成年小鼠不同组织中的作用，我们构建了miR-22敲除小鼠模型，并对肌肉、心脏、肝脏、肾脏及白色脂肪组织的表达谱进行了分析。