Inherited damaging mutations in immune-related genes favour the development of genetically heterogeneous synchronous colorectal cancer.
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https://www.omicsdi.org/dataset/ega/EGAS00001001461
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资源简介:
Synchronous colorectal cancers are physically separated tumours that develop simultaneously in the intestine. To understand how common genetic and environmental backgrounds influence the development of multiple tumours, we conduct a genome-wide comparative analysis of somatic alterations of 20 syCRCs from 10 patients. We show that syCRCs have independent genetic origins, acquire discordant somatic alterations, and follow different clonal developments.EGA study EGAS00001001461
创建时间:
2017-07-26



