Frequency of rescue of cleft palate by muscimol in Gad1-/- and Viaat-/- mice.

The frequency of cleft palate is expressed as the number of E17.5 day mice exhibiting a cleft palate over the total number examined for that injection condition.The frequency of cleft palate in Gad1-/- E17.5 mice is 100%. In the case of the Viaat mutant mice we have examined over 200 newborn or late gestation embryos and the cleft palate phenotype is present in 100% of the offspring.aPBS injected controls were Viaat +/− dams from ViaatlacZ heterozygote intercrosses.